Functional Biochemistry

due to the insufficient A patient has a mental disorder synthesis of gamma-aminobutyric acid in the brain. Such pathological changes might be caused by the deficiency of the following vitamin:

A 46-year-old patient was found to have hyperactivity of creatine kinase in his blood serum. What kind of pathology can be suspected?

The second stage of detoxification involves joining certain chemical compounds with functional groups of toxins. Select one such compound:

Natural peptides can perform various functions. What bioactive peptide is a major antioxidant and performs coenzyme functions?

Patients with severe depression demonstrate decreased serotonin levels in brain and cerebrospinal fluid. What amino acid is a serotonin precursor?

A sanitary-epidemic station employee has been poisoned when the premises were processed with an organophosphorus insecticide. What enzyme is inhibited by organophosphorus compounds?

Indican excretion is a diagnostic criterion of intensified protein putrefaction in the intestine. Name the end product of tryptophan “decay” occurring in the large intestine:

Coumarins, vitamin K antagonists, suppress the processes of blood coagulation. What protein synthesis is blocked by coumarins?

A patient with high risk of hemorrhages is recommended to take vicasol (menadione) by his physician. This drug is the structural analog of:

Any damage to the patient’s vessels results in persistent hemorrhage. Blood clotting factor VIII is in deficiency in the patient’s blood. What disease does this patient suffer from?

A patient with acute myocardial infarction received anticoagulation therapy. What compound will have anticoagulation effect?

A 46-year-old patient presents with hyperactivity of creatine kinase in his blood serum. What pathology can be suspected?